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Amphiregulin (AREG) stimulation of EGFR signaling by breast tumor cells contributes to tumor cell colonization of the bone, in part through induction of PTHrP expression. From Sem Cell Dev Biol 21 (09): 951-60 (2010).

Ethanol (EtOH) can stimulate processing of EGF family peptide growth factors, leading to increased EGF receptor signaling. From Breast Cancer Targets Ther 1 (01): 31-38 (2009).