Embedded Files
2025-04-04 - Congratulations to Markelle Scott for being awarded a 2025-26 Auburn University Undergraduate Research Fellowship! Photo. Photo.
2025-03-31 - The Riese lab mourns the "death" of its beloved BioRad 400 power supply, which had been used to run countless gels since the Riese lab inherited it in July 1997. Photo.
2025-03-29 - David presented an overview of work in the Riese lab at the 2025 Harrison College of Pharmacy Spring Alumni Event. Poster. DOI.
2025-03-26 - Riese lab member Vipasha Dwivedi gave a wonderful oral presentation ("ERBB4 Heterodimers Drive BRAF WT Melanoma Cell Lines") at the Auburn University Student Research Symposium. Great job, Vipasha! Presentation. DOI. Picture of Vipasha.
2025-03-26 - The Riese lab had FIVE posters at the Auburn University Student Research Symposium. Congratulations to the presenters and the rest of the Riese lab for their contributions to this terrific work.
Rees Cooke - "ERBB4 Heterodimers Appear to Drive BRAF WT Melanoma Cell Lines" - Poster. Picture of Rees. DOI.
Nick DeFeo and Tori Huffman - "Are Monoclonal Antibodies Against ERBB2 Effective Against ERBB2- and ERBB4-Dependent BRAF-WT Melanoma Cell Lines?" - Poster. Picture of Tori and Nick. DOI.
Teigen Nelson - "Gain-of-Function Mutant Alleles of the ERBB4 Gene May Drive a Gender Disparity in BRAF WT Melanomas" - Poster. Picture of Teigen. DOI.
Markelle Scott - "Using Mutations in a Dimerization Interface of ERBB4 and ERBB2 to Elucidate the Role of ERBB4-ERBB2 Heterodimers in BRAF WT Melanomas" - Poster. Picture of Markelle. DOI.
Ella Wilson - "Are Endogenous ERBB4 Ligands Necessary for the Proliferation of BRAF-WT Melanoma Cell Lines?" - Poster. Picture of Ella. DOI.
2025-03-06 - Riese lab member Ella Wilson (P1 PharmD student) received the Harrison College of Pharmacy PharmD Student Research award. Congratulations to Ella!
2025-03-06 - Riese lab member Tate Reese (P3 PharmD student) received a Harrison College of Pharmacy Professionalism award. Congratulations to Tate!
2025-03-03 - Auburn University freshmen Hayden Eldridge, Deirdre Smith, and Andra Tylke have joined the Riese Lab. Welcome!
2025-01-24 - Riese lab members Markelle Scott (sophomore) and Tori Huffman (P2 PharmD student) were selected by the Harrison College of Pharmacy to compete for "Gateway to Research" Fellowships from the American Foundation for Pharmaceutical Education.
2025-01-14 - Riese lab member Markelle Scott (sophomore) had his abstract accepted by the National Conference on Undergraduate Research in Pittsburgh, PA. Markelle's poster presentation is scheduled for April 8. Congratulations, Markelle!
2025-01-05 - David and the Department of Drug Discovery and Development faculty presented DDD strategic priorities to the HCOP Executive Committee.
2024-12-31 - The Riese laboratory submitted an annual RPPR progress report in support of NIH grant R15CA280767.
2024-12-09 - P4 PharmD student Madison Zelon presented Riese lab research findings at the ASHP Midyear meeting. Poster. Picture of Madison.
2024-12-07 - In partial fulfillment of the requirements of an Auburn University Undergraduate Research Fellow, Markelle Scott submitted an action photo and video.
2024-11-08 - Graduate student Dr. Vipasha Dwivedi presented Riese lab research findings at the Southeastern Region Society of Toxicology meeting. Poster.
2024-10-22 - P2 PharmD student Chloé Dion and graduate student Dr. Vipasha Dwivedi presented an overview of research in the Riese laboratory at the Auburn University Faculty Showcase for Undergraduate Research. Poster. Picture of Chloé.
2024-10-16 - David and Dr. Gary Piazza gave outreach presentations at the Auburn University Osher Lifelong Learning Institute. David's presentation was titled "Introduction to Cancer Biology and Genetics." Presentation. DOI.
2024-10-02 - David presented recent Riese lab research findings ("Do ERBB4 Heterodimers Drive BRAF-WT, RAS/NF1-Mutant Melanomas?") at an Auburn University College of Veterinary Medicine Pathobiology Department Research Seminar. Presentation. DOI.
2024-09-18 - David presented recent Riese lab research findings ("Melanoma Research in the Riese Lab") at the AU HCOP NCODA chapter meeting. Presentation. DOI.
2024-08-26 - The Riese lab, in collaboration with Department of Drug Discovery faculty members Gary Piazza, Adam Keeton, and Yulia Maxuitenko, submitted a US Army (USAMRDC) Melanoma Research Program grant application entitled: "Do ERBB4-ERBB2 heterodimers drive BRAF WT, RAS/NF1 mutant melanomas?" Application. Good luck!
2024-08-23 - The Riese lab, led by PhD student Dr. Vipasha Dwivedi, recently published a preprint at BioRxiv entitled: "Human melanoma cell lines that possess wild-type BRAF alleles but are dependent on ERBB4 and ERBB2." Publication. DOI.
2024-08-19 - The Riese lab is delighted to add new Pharmaceutical Sciences PhD student Teigen Nelson to the team. Teigen recently earned an undergraduate degree from the Montana State University, where she conducted undergraduate research in plant genetics. Welcome to Auburn, Teigen!
2024-06-27 - David presented a poster at the National Cancer Institute Division of Cancer Biology R15 Investigator Workshop (Bethesda, MD) entitled "ERBB4 Heterodimers Appear to Drive BRAF WT Melanoma Cell Lines". Poster.
2024-05-13 - Riese lab undergraduate researcher Markelle Scott and David have been awarded a diversity supplement to the NIH/NCI grant application R15CA280767. Congratulations to Markelle and David!
2024-04-09 - Graduate Student Dr. Vipasha Dwivedi presented a poster at the AACR Annual Meeting (San Diego, CA) entitled "ERBB4 Heterodimers Appear to Drive BRAF WT Melanoma Cell Lines". Poster
2024-04-04 - Riese lab undergraduate researcher Markelle Scott has been awarded a 2024-25 Auburn University Undergraduate Research Fellowship to support his work in the Riese laboratory. Congratulations to Markelle!
2024-04-01 - Teigen Nelson and Dr. Niusha Raeesian have accepted offers of admission to the Auburn University Pharmaceutical Sciences graduate program (Pharmacology option) and will be joining the Riese lab this fall to conduct their thesis/dissertation research. Congratulations to Teigen and Niusha!
2024-03-13 - Riese lab alumnus (and soon-to-be AU HCOP PharmD alumnus) Jessica Vail has been matched to a PGY1 residency at the DCH Regional Medical Center in Tuscaloosa, Alabama. Congratulations to Jessica on this well-deserved opportunity!
2024-03-07 - David presented a University of Alabama - Birmingham O'Neal Comprehensive Cancer Center/ Cancer Biology and Immunology Seminar - "Do ERBB4 Heterodimers Drive BRAF WT Melanomas?" PowerPoint Slides.
2024-02-15 - The Riese Lab has published a report in Protocols.io that describes our protocol for stable transfection of plasmid DNA into adherent rodent cells using calcium phosphate. Publication.
2024-02-12 - The Riese Lab has published a report in Protocols.io that describes the generation of recombinant retroviral expression vectors that contains the hygromycin resistance gene, as well as the cDNAs for the mature Epidermal Growth Factor (EGF), Transforming Growth Factor alpha (TGFalpha), Neuregulin 2beta (NRG2beta), and the Q43L mutant of NRG2beta. These constructs can be used to study the effects of ligand-induced ERBB receptor signaling on human tumor cell lines. Publication.
2024-02-08 - The Riese lab has published a report in Protocols.io that describes the generation of recombinant retroviral expression vectors that contain the dominant negative mutant alleles of EGFR and ERBB2. Publication.
2023-12-22 - NIH/NCI grant application 1R15CA280767 has been funded, effective January 1, 2024! Congratulations to the Riese and Arnold labs for this tremendous achievement!
2023-11-28 - Riese lab undergraduate researcher Markelle Scott has been recognized as a member of the inaugural cohort of Auburn University Melton Scholars. Photo of the cohort - Markelle is in the second row, second from the left. Congratulations to Markelle!
2023-11-27 - David presented an Auburn University Department of Drug Discovery Seminar - "ERBB4 Heterodimers Drive BRAF WT Melanomas" PowerPoint Slides.
2023-10-18 - David presented a Harrison College of Pharmacy NCODA Seminar - "Do ERBB4 Heterodimers Drive BRAF WT Melanomas?" PowerPoint Slides
2023-08-31 - The Riese Lab has published a report in Protocols.io that describes the reagents, including media and selection agents, used for eukaryotic cell culture in our laboratory. Publication.
2023-08-23 - The Riese Lab has published a report in Protocols.io that describes the generation of a recombinant retroviral expression vector that contains the hygromycin resistance gene. This paper also describes the generation of derivatives that permit the ectopic expression of EGFR, ERBB2, and ERBB3. Thus, the tools described in this paper can be used in combination with those described in our prior Protocols.io publication to study the effects of ERBB receptor heterodimerization. Link to publication.
2023-08-22 - The Riese Lab has published a report in Protocols.io that describes the generation of recombinant retroviral expression vectors that permit the ectopic expression of the neomycin resistance gene and EGFR, ERBB2, ERBB3, or ERBB4 in both murine and human cells. These tools can be used to study the function of these oncogenes. Publication.
2023-08-09 - NIH/NCI grant application 1R15CA280767 has been reviewed and received an impact score of 21. We are hopeful that this application will be funded.
2023-06-26 - The Riese Lab published updates to the following medRXiv preprints:
2023-04-26 - The Riese Lab celebrated the end of the semester with a lab dinner at The Depot. Congratulations to Lauren Lucas, who is now a postdoc in Bill Tansey's lab at the Vanderbilt-Ingram Cancer Center; Elizabeth Knerr, who is entering the postgraduate Medical Laboratory Science Program at Vanderbilt University; Joelle Woggerman, who is entering the Molecular Pharmacology and Therapeutics PhD program at the University of Minnesota; and Jessica Vail, who is beginning her APPE rotations as a fourth-year student in the Auburn University PharmD program. Again, congratulations to Lauren, Elizabeth, Joelle, and Jessica!
2023-04-11 - David Riese interviewed for the position of Senior Vice President for Research and Economic Development at Auburn University. Letter of interest. Presentation.
2023-02-20 - Graduate student Vipasha Dwivedi presented her dissertation studies at a Department of Drug Discovery and Development seminar. Presentation.
2023-01-13 - Graduate student Lauren Lucas passed the oral defense of her doctoral dissertation research! Congratulations Lauren! Presentation.
2022-12-12 - David Riese presented our research findings ("ERBB4 is a Driver of BRAF-WT Melanoma") at a joint meeting of the American Association for Cancer Research and the Japanese Cancer Association. Poster.
2022-11-08 - Graduate student Lauren Lucas submitted a draft of her doctoral dissertation ("ERBB4 is a Driver of BRAF-WT Melanoma") to the Auburn University Graduate School. The Graduate School approved the format of her dissertation and Lauren is authorized to complete and defend her dissertation. Congratulations, Lauren!
2022-11-01 - Graduate student Lauren Lucas has accepted a postdoc position in Bill Tansey's research team at the Vanderbilt-Ingram Cancer Center/Vanderbilt University School of Medicine. Congratulations, Lauren! Presentation.
2022-10-28 - Undergraduate student Joelle Woggerman presented work ("ERBB4 Drives BRAF-WT Melanomas") from the Riese laboratory in partial fulfillment of her undergraduate research course requirements. Many thanks to graduate student Lauren Lucas for helping Joelle prepare her seminar. Wonderful job, Joelle! Presentation.
2022-10-26 - The Riese Laboratory presented its research findings ("ERBB4 is a Driver of BRAF-WT Melanoma") at the University of Alabama-Birmingham O'Neal Comprehensive Cancer Center Retreat. Many thanks to graduate student Lauren Lucas for preparing the poster, many thanks to Lauren and fellow graduate student Vipasha Dwivedi for manning the poster, and many thanks to the UAB O'Neal Comprehensive Cancer Center for allowing us the opportunity to present our work. Poster.
2022-10-05 - David Riese gave a presentation ("Publishing Your Research: A Case Study") as part of the Auburn University graduate student development program. Presentation.
2022-08-31 - David Riese's teaching effectiveness in the Oncology section of ILE9 was evaluated by the Harrison College of Pharmacy Division of Faculty Affairs. David received an overall score of 20 out of 20. Report.
2022-06-08 - David Riese gave a presentation ("What is Graduate Study and Why Should You Be Interested") as part of the Auburn University Harrison College of Pharmacy high school student pharmacy camp. Presentation.
2022-04-19 - The Riese Laboratory presented its research findings ("ERBB4 is a Driver of BRAF-WT Melanoma") at the Auburn University BMES Showcase. Poster.
2022-04-08 - The Riese Laboratory presented its research findings ("ERBB4 is a Driver of BRAF-WT Melanoma") at the American Association for Cancer Research Annual Meeting in New Orleans, LA. Poster.
2022-04-05 - David Riese gave a professional development seminar ("What Is R and Why You Should Care") to the Auburn University chapter of the American Association of Pharmaceutical Sciences. Link to presentation.
2022-03-28 - Graduate students Lauren Lucas, Vipasha Dwivedi, and Rania Mohamedelhassan presented their research findings at the Auburn University Student Research Symposium. Congratulations and thanks to Lauren, Vipasha and Rania for their hard work. Link to Lauren's oral presentation. Link to Vipasha's poster presentation. Link to Rania's poster presentation.
2022-02-16 - David Riese gave a professional development seminar ("Publishing Your Research: A Case Study" to Auburn University Graduate Students. Presentation. Zip archive of references.
2022-02-14 - Graduate student Lauren Lucas presented her research findings ("ERBB4 is a Driver of BRAF-WT Melanoma") in an Auburn University Department of Drug Discovery and Development seminar. Great job, Lauren! Presentation.
2022-01-01 - The Riese Lab has published a report in Pharmacological Reviews that reviews the role that ERBB4 appears to play in human malignancies. The lead author of this work is Lauren Lucas. Congratulations to Lauren and the rest of the team! Publication. Pubmed entry.
2021-10-28 - The Riese Lab has published a report in Protocols.io that describes an in silico strategy for determining whether a set of missense mutations found in a gene of interest are not randomly distributed. This strategy could be used to determine whether these mutations function as tumor drivers. The lead author of this work is Richard Cullum. Congratulations to Richard! Publication.
2021-05-01 - Dr. Vipasha Dwivedi has been accepted as a full-time student in the Pharmacology Option of the Pharmaceutical Sciences PhD program. Vipasha earned an MBBS from NIMS University in India. She completed internship and residency training in India, after which she practiced at the Nav Bharti Industrial Training Institute in India. Vipasha is pursuing dissertation studies in the Riese lab. Congratulations and good luck, Vipasha!
2020-12-30 - The Riese Lab has published a report in PLOS One that describes the development and deployment of a high-throughput screen for candidate ERBB4 antagonists. The lead authors of this work are Richard Cullum and Lauren Lucas. Congratulations to Richard, Lauren, and the rest of the team! Publication. Pubmed entry.
2020-12-03 - David Riese has collaborated with Jianzhong Shen's laboratory on a review article in Frontiers in Pharmacology on the role of the chemokine CXCL12/CXCR4/CXCR7 axis in cancer. Congratulations to graduate student Yi Shi of the Shen lab for her outstanding contributions to this work. Publication. Pubmed entry.
2020-12-01 - David Riese has been appointed to an affiliate faculty position at the O'Neal Comprehensive Cancer Center at the University of Alabama-Birmingham. David is affiliated with the Cancer Biology and Immunology Research Program. Congratulations, David!
2020-09-30 - Former Riese lab graduate student Richard Cullum has been named one of six recipients of the 2020 Auburn University Graduate School Distinguished Dissertation Awards. This award is based on the significance of Richard's dissertation research and its methodological and substantive quality. Congratulations, Richard!
2020-08-01 - Dr. Vipasha Dwivedi has joined the Riese laboratory as an unpaid, part-time graduate student. Vipasha earned an MBBS from NIMS University in India. She completed internship and residency training in India, after which she practiced at the Nav Bharti Industrial Training Institute in India. Welcome, Vipasha!
2020-05-06 - Riese lab graduate student Richard Cullum has been awarded a PhD in Chemical Engineering from Auburn University. Richard's doctoral dissertation is entitled "Melanoma drug discovery: Prioritization of candidate melanoma driver mutations in the ERBB4 receptor tyrosine kinase gene and identification of novel molecules that disrupt ERBB4 signaling." Congratulations, Richard!
2020-04-07 - Riese lab graduate student Richard Cullum has been recognized for his efforts in developing the first commercially available COVID-19 test available in the State of Alabama. This work, done at Assurance Scientific Labs, leverages Richard's training in assay design and validation at Auburn University. Congratulations, Richard!
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